A variety of symptoms associated with taking lansoprazole could warrant a call to your GP see more...

Serious side effects of taking lansoprazole include:

  • Itchy red skin rash and joint pain which could indicate a condition known as subacute cutaneous lupus erythematosus
  • Severe or persistent diarrhoea which could be a sign of an inflamed bowel
  • Stomach pain that gets worse which could indicate an inflamed liver or pancreas

Stomach pain can also be a common side effect that affects more than one in 100 people taking lansoprazole. While this pain may be minor in some cases, the NHS cautions that if you experience stomach pain that seems to be worsening, then you should call a doctor or dial 111.

The report emphasises that such stomach discomfort "can be a sign of an inflamed liver or pancreas". Additionally, if you experience severe or frequent diarrhoea while taking the PPI, it could indicate an inflamed bowel.

It is crucial to understand that these serious side effects are extremely rare for people taking lansoprazole, typically affecting fewer than one in 1,000 people. If you have concerns about taking lansoprazole or its associated side effects, it is generally recommended to consult a pharmacist or your GP for further guidance.

While these side effects may be serious, they usually will not necessitate a 999 call. However, you might need to dial 999 if you exhibit any of the following symptoms, some of which could indicate a severe allergic reaction to lansoprazole:

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  • Tight feeling in the throat
  • Struggling to swallow
  • Someone faints and cannot be woken up
  • Very fast breathing
  • Struggling to breathe or feeling like you're gasping for air
  • Sudden confusion, dizziness, or drowsiness
  • Sudden swelling of lips, mouth, tongue, or throat
  • Skin, lips, or tongue turn blue, pale, or grey
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